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Article

Prognostic value of JAK3 promoter methylation and mRNA expression in clear cell renal cell carcinoma

3 Dec 2021

Abstract excerpt

Janus kinase 3 (JAK3) is a well-established oncogene in clear cell renal cell carcinoma (ccRCC). The methylation status of oncogene promoters has emerged as biomarkers for cancer diagnosis and prognosis. This study aims to investigate the biological and clinical significance of JAK3 promoter methylation in ccRCC. We analyzed the relationship of JAK3 promoter methylation with its mRNA expression, overall survival,...

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PMID: 36100323
DOI: 10.1016/j.jare.2021.11.016

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