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Article

A Mouse Model for Tuberculosis Combined With Inhalable Imiquimod-PLGA Nanocomposite Particles Based on Macrophage Phenotype.

In vivo (Athens, Greece) - 1 Jan 2000

Nii Teruki, Takizawa Shunsuke, Akita Tomomi, Yamashita Chikamasa, Takeuchi Issei, Makino Kimiko

Abstract excerpt

BACKGROUND/AIM: In vivo models of tuberculosis are effective tools for developing new drugs. The objective of this study was to prepare in vivo models for tuberculosis by utilizing nanocomposite particles (NCPs) containing imiquimod-loaded poly(lactic-co-glycolic acid) nanoparticles. MATERIALS AND METHODS: NCPs were prepared from dichloromethane with imiquimod and poly(lactic-co-glycolic acid) using a spray...

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Identifiers

PMID: 36099123
DOI: 10.21873/invivo.12942
PMCID: PMC9463881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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