Article
Self-supervised classification of subcellular morphometric phenotypes reveals extracellular matrix-specific morphological responses.
Scientific reports - 12 Sept 2022
Wong Kin Sun, Zhong Xueying, Low Christine Siok Lan, Kanchanawong Pakorn
Abstract excerpt
Cell morphology is profoundly influenced by cellular interactions with microenvironmental factors such as the extracellular matrix (ECM). Upon adhesion to specific ECM, various cell types are known to exhibit different but distinctive morphologies, suggesting that ECM-dependent cell morphological responses may harbour rich information on cellular signalling states. However, the inherent morphological complexity...
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