Article
Deleterious Mutations and the Rare Allele Burden on Rice Gene Expression.
Molecular biology and evolution - 1 Sept 2022
Lye Zoe, Choi Jae Young, Purugganan Michael D
Abstract excerpt
Deleterious genetic variation is maintained in populations at low frequencies. Under a model of stabilizing selection, rare (and presumably deleterious) genetic variants are associated with increase or decrease in gene expression from some intermediate optimum. We investigate this phenomenon in a population of largely Oryza sativa ssp. indica rice landraces under normal unstressed wet and stressful drought field...
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