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Article

Deleterious Variants in Asian Rice and the Potential Cost of Domestication.

Molecular biology and evolution - 1 Apr 2017

Liu Qingpo, Zhou Yongfeng, Morrell Peter L, Gaut Brandon S

Abstract excerpt

Many SNPs are predicted to encode deleterious amino acid variants. These slightly deleterious mutations can provide unique insights into population history, the dynamics of selection, and the genetic bases of phenotypes. This is especially true for domesticated species, where a history of bottlenecks and selection may affect the frequency of deleterious variants and signal a "cost of domestication". Here, we...

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PMID: 28087781
DOI: 10.1093/molbev/msw296

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