Article
The Placenta Epigenome–Brain Axis: Placental Epigenomic and Transcriptomic Responses that Preprogram Cognitive Impairment
1 Aug 2022
Abstract excerpt
Aim: The placenta–brain axis reflects a developmental linkage where disrupted placental function is associated with impaired neurodevelopment later in life. Placental gene expression and the expression of epigenetic modifiers such as miRNAs may be tied to these impairments and are understudied. Materials & methods: The expression levels of mRNAs (n = 37,268) and their targeting miRNAs (n = 2083) were assessed...
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