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Article

The Dysfunctional Placenta Epigenome: Causes and Consequences

1 Oct 2012

Abstract excerpt

The placenta is a fetal-maternal endocrine organ responsible for ensuring proper fetal development throughout pregnancy. Adverse insults to the intrauterine environment often lead to expression level changes in placental genes, many of which are epigenetically regulated by DNA methylation, histone modifications and ncRNA interference. These epigenetic alterations may cause placental dysfunction, resulting in...

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Identifiers

PMID: 23130837
DOI: 10.2217/epi.12.49

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