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Coffee consumption and cancer risk: a Mendelian randomisation study.

Clinical nutrition (Edinburgh, Scotland) - 1 Oct 2022

Carter Paul, Yuan Shuai, Kar Siddhartha, Vithayathil Mathew, Mason Amy M, Burgess Stephen, Larsson Susanna C

Abstract excerpt

BACKGROUND: Coffee contains many bioactive chemicals and associations with cancer have been reported in observational studies. In this Mendelian randomisation (MR) study we investigated the causal associations of coffee consumption with a broad range of cancers. MATERIALS AND METHODS: Twelve independent genetic variants proxied coffee consumption. Genetically-predicted risk of any cancer (59,647 cases) and 22...

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Identifiers

PMID: 36067583
DOI: 10.1016/j.clnu.2022.08.019
PMCID: PMC7613623

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