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Within subject cross‐tissue analyzes of epigenetic clocks in substance use disorder postmortem brain and blood

3 Sept 2022

Abstract excerpt

There is a possible accelerated biological aging in patients with substance use disorders (SUD). The evaluation of epigenetic clocks, which are accurate estimators of biological aging based on DNA methylation changes, has been limited to blood tissue in patients with SUD. Consequently, the impact of biological aging in the brain of individuals with SUD remains unknown. In this study, we evaluated multiple...

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PMID: 36056652
DOI: 10.1002/ajmg.b.32920

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