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DNA methylation age is accelerated in alcohol dependence

5 Sept 2018

Abstract excerpt

Alcohol dependence (ALC) is a chronic, relapsing disorder that increases the burden of chronic disease and significantly contributes to numerous premature deaths each year. Previous research suggests that chronic, heavy alcohol consumption is associated with differential DNA methylation patterns. In addition, DNA methylation levels at certain CpG sites have been correlated with age. We used an epigenetic clock to...

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PMID: 30185790
DOI: 10.1038/s41398-018-0233-4

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