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Joint exposure to positive affect, life satisfaction, broad depression, and neuroticism and risk of cardiovascular diseases: A prospective cohort study.

Atherosclerosis - 1 Oct 2022

Sun Ying, Zhang Haojie, Wang Bin, Chen Chi, Chen Yingchao, Chen Yi, Xia Fangzhen, Tan Xiao, Zhang Jihui, Li Qing, Qi Lu, Lu Yingli, Wang Ningjian

Abstract excerpt

BACKGROUND AND AIMS: Psychologic wellbeing can impact cardiovascular health. We aimed to evaluate the joint association of multiple psychologic wellbeing factors with cardiovascular diseases (CVD) and examine whether this association was modified by genetic susceptibility. METHODS: In the UK Biobank, 126,255 participants free of CVD (coronary heart disease [CHD], stroke, and heart failure [HF]) at baseline, who...

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PMID: 36055801
DOI: 10.1016/j.atherosclerosis.2022.08.007

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