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Article

CASC11 and PVT1 spliced transcripts play an oncogenic role in colorectal carcinogenesis

16 Aug 2022

Abstract excerpt

Cancer is fundamentally a genetic disorder that alters cellular information flow toward aberrant growth. The coding part accounts for less than 2% of the human genome, and it has become apparent that aberrations within the noncoding genome drive important cancer phenotypes. The numerous carcinogenesis-related genomic variations in the 8q24 region include single nucleotide variations (SNVs), copy number variations...

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PMID: 36052265
DOI: 10.3389/fonc.2022.954634

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