Article

Long Noncoding RNA PVT1 Predicts Poor Prognosis and Promotes the Progression of Colorectal Cancer Through the MiR-24-3p/NRP1 Axis in Zebrafish Xenografts

2022-02-28

Abstract excerpt

<h4>Background: </h4> Long noncoding RNAs (lncRNAs) play important roles in the progression of human cancer. It is reported lncRNA plasmacytoma variant translocation 1 (PVT1) is involved in colorectal cancer (CRC), however, the underlying mechanism remains to be explored deeply, especially by in vivo models. <h4>Methods: </h4> The expression level of PVT1 in CRC tissues was analyzed in TCGA and GEO database. The p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8dd38b82-db80-54e9-a189-1e2db67721ae
DOI: 10.21203/rs.3.rs-1353449/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Long Noncoding RNA PVT1 Predicts Poor Prognosis and Promotes the Progression of Colorectal Cancer Through the MiR-24-3p/NRP1 Axis in Zebrafish XenograftsDOI 10.21203/rs.3.rs-1353449/v1Read

Long noncoding RNA plasmacytoma variant translocation 1 promotes progression of colorectal cancer by sponging microRNA‐152‐3p and regulating E2F3/MAPK8 signalingSemantic proximity Read

LncRNA PVT1 facilitated growth and metastasis of colorectal cancer by sponging with miR-3619-5p to regulate TRIM29 expressionSemantic proximity Read

PVT1 Long Non-coding RNA in Gastrointestinal CancerSemantic proximity Read

Long Noncoding RNA PVT1 Promotes EMT and Cell Proliferation and Migration Through Downregulating p21 in Pancreatic Cancer CellsSemantic proximity Read

Long Non-coding RNA PVT1 Promotes Cell Proliferation and Migration by Silencing ANGPTL4 Expression in CholangiocarcinomaSemantic proximity Read

LncRNA NALT1 promotes colorectal cancer progression via targeting PEG10 by sponging microRNA-574-5pSemantic proximity Read

Identification of LncRNA NUSAP1 as a Novel Biomarker for Colorectal Cancer Progression and MetastasisSemantic proximity Read

Long non-coding RNA BCYRN1 exerts an oncogenic role in colorectal cancer through regulating miR-204-3p/KRAS axisSemantic proximity Read

lncRNA PVT1 identified as an independent biomarker for prognosis surveillance of solid tumors based on transcriptome data and meta-analysisSemantic proximity Read

PTOV1 is a Prognostic Biomarker and Correlated with Poor Progression in Colorectal CancerSemantic proximity Read

Long Noncoding RNA PVT1 Promotes Breast Cancer Proliferation and Metastasis by Binding mIR-128-3p and UPF1Semantic proximity Read

CASC11 and PVT1 spliced transcripts play an oncogenic role in colorectal carcinogenesisSemantic proximity Read