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Article

Single-cell immune ecosystem and metabolism reprogramming imprinted by psoriasis niche

1 Aug 2022

Abstract excerpt

Background: A major challenge of psoriasis is its dysfunctional immune niche. Remarkable gaps remain in understanding how immune cell state transitions are linked to clinical outcomes in psoriasis. Thus, there is a pressing need to discover immunomodulatory programs governing psoriasis progression. Methods: Here, by using the state-of-the-art single-cell RNA-sequencing (RNA-seq) data, we observed the unique...

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PMID: 36034981
DOI: 10.21037/atm-22-1810

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