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Article

An iterative gene-editing strategy broadens eIF4E1 genetic diversity in Solanum lycopersicum and generates resistance to multiple potyvirus isolates.

Plant biotechnology journal - 1 May 2023

Kuroiwa Kyoka, Danilo Benoit, Perrot Laura, Thenault Christina, Veillet Florian, Delacote Fabien, Duchateau Philippe, Nogué Fabien, Mazier Marianne, Gallois Jean-Luc

Abstract excerpt

Resistance to potyviruses in plants has been largely provided by the selection of natural variant alleles of eukaryotic translation initiation factors (eIF) 4E in many crops. However, the sources of such variability for breeding can be limited for certain crop species, while new virus isolates continue to emerge. Different methods of mutagenesis have been applied to inactivate the eIF4E genes to generate virus...

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PMID: 36715107
DOI: 10.1111/pbi.14003
PMCID: PMC10106848

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An iterative gene-editing strategy broadens eIF4E1 genetic diversity in Solanum lycopersicum and generates resistance to multiple potyvirus isolates.PMID 36715107Read ↗

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