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Article

Predominance of the Rare EGFR Mutation p.L861Q in Tunisian Patients with Non-Small Cell Lung Carcinoma.

Genes - 22 Aug 2022

Abdelmaksoud-Dammak Rania, Ammous-Boukhris Nihel, Saadallah-Kallel Amèna, Charfi Slim, Khemiri Souhir, Khemakhem Rim, Kallel Nesrin, Ben Kridis-Rejeb Wala, Sallemi-Boudawara Tahya, Khanfir Afef, Yangui Ilhem, Daoud Jamel, Mokdad-Gargouri Raja

Abstract excerpt

Objectives: Several new cancer therapies targeting signaling pathways involved in the growth and progression of cancer cells were developed as personalized medicine. Our study aimed to identify epidermal growth factor receptor (EGFR) mutations for TKI treatment in non-small-cell lung cancer (NSCLC) Tunisian patients. Methods: Analysis of the TKI sensitivity mutations in exons 18 to 21 of the EGFR gene and exon 15...

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Identifiers

PMID: 36011410
DOI: 10.3390/genes13081499
PMCID: PMC9407939

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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