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Placental DNA methylation changes in gestational diabetes mellitus

21 Aug 2022

Abstract excerpt

In this study, we investigated the association between altered methylation in the maternal placenta and hyperglycaemia and explored the epigenetic mechanisms underlying gestational diabetes mellitus (GDM). Reduced representation bisulphite sequencing (RRBS) and RNA sequencing (RNA-seq) were performed on placental tissues obtained from women with GDM and healthy controls. Further, pyrosequencing, correlation...

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PMID: 35993280
DOI: 10.1080/15592294.2022.2110193

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