Article
Study on the relationship between DNA methylation of target CpG sites in peripheral blood and gestational diabetes during early pregnancy.
Scientific reports - 14 Oct 2021
Wang Xiaolei, Huang Jin, Zheng Yixiang, Long Sisi, Lin Huijun, Zhang Na, Tian Mengyuan, Wu Xinrui, An Rongjing, Ma Shujuan, Tan Hongzhuan
Abstract excerpt
Genome-wide DNA methylation profiling have been used to find maternal CpG sites related to the occurrence of gestational diabetes mellitus (GDM). However, none of these differential sites found has been verified in a larger sample. Here, our aim was to evaluate whether first trimester changes in target CpG sites in the peripheral blood of pregnancy women predict subsequent development of GDM. This nested...
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