Article
Cancer stem cells - new and potentially important targets for the therapy of oral squamous cell carcinoma.
Oral diseases - 1 Sept 2006
Costea D E, Tsinkalovsky O, Vintermyr O K, Johannessen A C, Mackenzie I C
Abstract excerpt
There is increasing evidence that the growth and spread of cancers is driven by a small subpopulation of cancer stem cells (CSCs) - the only cells that are capable of long-term self-renewal and generation of the phenotypically diverse tumour cell population. Current failure of cancer therapies may be due to their lesser effect on potentially quiescent CSCs which remain vital and retain their full capacity to...
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