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Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study

16 Aug 2022

Abstract excerpt

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease characterised by progressive scarring leading to alveolar stiffness, reduced lung capacity, and impeded gas transfer. We aimed to identify genetic variants associated with declining lung capacity or declining gas transfer after diagnosis of IPF. METHODS: when meta-analysing across all discovery and follow-up studies, had consistent...

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PMID: 35985358
DOI: 10.1016/s2213-2600(22)00251-x

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