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Article

Frequency of germline genetic variants in women with a personal or family history of breast cancer from Brazil.

Molecular biology reports - 1 Oct 2022

Pereira Júlia Zanon, Carneiro Juliana Garcia, Vieira Mariana Sousa, Valente Bruna Mattioly, de Oliveira Pâmella Zorzan, Mello Carolina Lins, de Campos Caroline Leonel Vasconcelos, Gomes Karina Braga

Abstract excerpt

BACKGROUND: About 5-10% of breast cancer cases are related to genetic and hereditary factors. The application of Next Generation Sequencing (NGS) in oncology has allowed the identification of genetic variants present in several genes related to the increased risk of breast cancer. This study aimed to determine the frequency of germline genetic variants in patients with a family and/or personal history of breast...

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PMID: 35980532
DOI: 10.1007/s11033-022-07840-0

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