Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline variants of Brazilian women with breast cancer and detection of a novel pathogenic ATM deletion in early-onset breast cancer.

Breast cancer (Tokyo, Japan) - 1 Mar 2021

Bandeira Gabriel, Rocha Katia, Lazar Monize, Ezquina Suzana, Yamamoto Guilherme, Varela Monica, Takahashi Vanessa, Aguena Meire, Gollop Thomaz, Zatz Mayana, Passos-Bueno Maria Rita, Krepischi Ana, Okamoto Oswaldo Keith

Abstract excerpt

BACKGROUND: It is estimated that 5-10% of breast cancer cases are hereditary. The identification of pathogenic germline variants allows individualized preventive health care, improvement of clinical management and genetic counseling. Studies in ethnically admixed Latin American populations have identified regions with increased frequency of deleterious variants in breast cancer predisposing genes. In this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia Telangiectasia Mutated Proteins
Share to Brazil

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to BRCA1 Protein

Share to BRCA2 Protein

Share to Genetic Heterogeneity

Share to Germ Cells

Share to Germ-Line Mutation

Share to Ovarian Neoplasms

Source

Identifiers

PMID: 32986223
DOI: 10.1007/s12282-020-01165-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline variants of Brazilian women with breast cancer and detection of a novel pathogenic ATM deletion in early-onset breast cancer.PMID 32986223Read ↗

The spectrum of BRCA1 and BRCA2 alleles in Latin America and the Caribbean: a clinical perspective.Semantic proximity Read ↗

Germline molecular data in hereditary breast cancer in Brazil: Lessons from a large single-center analysis.Semantic proximity Read ↗

Hereditary Breast Cancer in the Brazilian State of Ceará (The CHANCE Cohort): Higher-Than-Expected Prevalence of Recurrent Germline Pathogenic VariantsSemantic proximity Read ↗

Molecular Characterization of Hereditary Breast and Ovarian Cancer Patients from a Public Precision Medicine Service in the Southeast Brazilian PopulationSemantic proximity Read ↗

Frequency of germline genetic variants in women with a personal or family history of breast cancer from Brazil.Semantic proximity Read ↗

Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene.Semantic proximity Read ↗

Hereditary breast cancer next-generation sequencing (NGS) panel evaluation in the south region of Brazil: a novel<i>BRCA2</i>candidate pathogenic variant is reportedSemantic proximity Read ↗

Germline mutations of breast cancer susceptibility genes through expanded genetic analysis in unselected Colombian patients.Semantic proximity Read ↗

BRCA1 and BRCA2 germline mutation analysis from a cohort of 1267 patients at high risk for breast cancer in Brazil.Semantic proximity Read ↗

Comprehensive Analysis of Germline Variants in Mexican Patients with Hereditary Breast and Ovarian Cancer SusceptibilitySemantic proximity Read ↗

Contribution of germline mutations in cancer predisposition genes to tumor etiology in young women diagnosed with invasive breast cancer.Semantic proximity Read ↗

Clinically Relevant Germline Mutations in a Cohort of Young Women with Breast Cancer: A Comprehensive Analysis of Hereditary-Cancer Genes from Whole-Exome SequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.