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Article

The Chicken A and E Blood Systems Arise from Genetic Variation in and around the Regulators of Complement Activation Region.

Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2022

Fulton Janet E, Drobik-Czwarno Wiola, Wolc Anna, McCarron Amy M, Lund Ashlee R, Schmidt Carl J, Taylor Robert L

Abstract excerpt

The tightly linked A and E blood alloantigen systems are 2 of 13 blood systems identified in chickens. Reported herein are studies showing that the genes encoding A and E alloantigens map within or near to the chicken regulator of complement activation (RCA) gene cluster, a region syntenic with the human RCA. Genome-wide association studies, sequence analysis, and sequence-derived single-nucleotide polymorphism...

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PMID: 35977798
DOI: 10.4049/jimmunol.2101010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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