Defining hierarchical protein interaction networks from spectral analysis of bacterial proteomes.

Abstract excerpt

Cellular behaviors emerge from layers of molecular interactions: proteins interact to form complexes, pathways, and phenotypes. We show that hierarchical networks of protein interactions can be defined from the statistical pattern of proteome variation measured across thousands of diverse bacteria and that these networks reflect the emergence of complex bacterial phenotypes. Our results are validated through...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacteria
• Share to Fimbriae, Bacterial