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Article

Activity-Dependent Induction of Younger Biological Phenotypes.

Advanced biology - 1 Dec 2022

Lissek Thomas

Abstract excerpt

In several mammalian species, including humans, complex stimulation patterns such as cognitive and physical exercise lead to improvements in organ function, organism health and performance, as well as possibly longer lifespans. A framework is introduced here in which activity-dependent transcriptional programs, induced by these environmental stimuli, move somatic cells such as neurons and muscle cells toward a...

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PMID: 35976161
DOI: 10.1002/adbi.202200119

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