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Molecular profiling of human non-small cell lung cancer by single-cell RNA-seq

12 Aug 2022

Abstract excerpt

BACKGROUND: Lung cancer, one of the most common malignant tumors, exhibits high inter- and intra-tumor heterogeneity which contributes significantly to treatment resistance and failure. Single-cell RNA sequencing (scRNA-seq) has been widely used to dissect the cellular composition and characterize the molecular properties of cancer cells and their tumor microenvironment in lung cancer. However, the transcriptomic...

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PMID: 35962452
DOI: 10.1186/s13073-022-01089-9

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