Article
Altered Thermal Behavior of Blood Plasma Proteome Related to Inflammatory Cytokines in Early Pregnancy Loss.
International journal of molecular sciences - 6 Aug 2022
Komsa-Penkova Regina, Danailova Avgustina, Krumova Sashka, Georgieva Galya, Giosheva Ina, Gartcheva Lidia, Iliev Ivan, Gartchev Emil, Kercheva Kameliya, Savov Alexey, Todinova Svetla
Abstract excerpt
Early pregnancy loss (EPL) is a relatively common pathology of which almost 50% of cases remain idiopathic. In the search for novel biomarkers, differential scanning calorimetry (DSC) is intensively used to characterize the thermodynamic behavior of blood plasma/serum proteome in health and disease. Herein, for the first time, we investigate the DSC denaturation profiles of blood plasma derived from patients...
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