Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-Contrast Stimulation Potentiates the Neurotrophic Properties of Müller Cells and Suppresses Their Pro-Inflammatory Phenotype.

International journal of molecular sciences - 3 Aug 2022

Zloh Miloslav, Kutilek Patrik, Stofkova Andrea

Abstract excerpt

High-contrast visual stimulation promotes retinal regeneration and visual function, but the underlying mechanism is not fully understood. Here, we hypothesized that Müller cells (MCs), which express neurotrophins such as brain-derived neurotrophic factor (BDNF), could be key players in this retinal plasticity process. This hypothesis was tested by conducting in vivo and in vitro high-contrast stimulation of adult...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain-Derived Neurotrophic Factor
Share to Gliosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Inflammation

Share to Phenotype

Share to Retina

Source

Open in PubMed Open full text

Identifiers

PMID: 35955747
DOI: 10.3390/ijms23158615
PMCID: PMC9369166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-Contrast Stimulation Potentiates the Neurotrophic Properties of Müller Cells and Suppresses Their Pro-Inflammatory Phenotype.PMID 35955747Read ↗

Regulation of Stem Cell Properties of Müller Glia by JAK/STAT and MAPK Signaling in the Mammalian RetinaSemantic proximity Read ↗

Müller cells and retinal angiogenesis: critical regulators in health and diseaseSemantic proximity Read ↗

Changes in Retinal Glial Cells with Age and during Development of Age-Related Macular DegenerationSemantic proximity Read ↗

Evaluation of Neuroprotective And Immunomodulatory Properties of Mesenchymal Stem Cells in An Ex-vivo Retinal Explant ModelSemantic proximity Read ↗

Genetic and epigenetic regulators of retinal Müller glial cell reprogrammingSemantic proximity Read ↗

AAV-mediated expression of proneural factors stimulates neurogenesis from adult Müller glia <i>in vivo</i> .Semantic proximity Read ↗

A journey into the retina: Müller glia commanding survival and deathSemantic proximity Read ↗

Proliferative Capacity and Neural Lineage Commitment of Müller Glia in the Adult Human RetinaSemantic proximity Read ↗

Development of Retinal AstrogliaSemantic proximity Read ↗

The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scarSemantic proximity Read ↗

Directed robust generation of functional retinal ganglion cells from Müller gliaSemantic proximity Read ↗

The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scarSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.