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Article

Evaluation of the role of KPNA2 mutations in breast cancer prognosis using bioinformatics datasets.

BMC cancer - 10 Aug 2022

Alnoumas Layla, van den Driest Lisa, Apczynski Zoe, Lannigan Alison, Johnson Caroline H, Rattray Nicholas J W, Rattray Zahra

Abstract excerpt

Breast cancer, comprising of several sub-phenotypes, is a leading cause of female cancer-related mortality in the UK and accounts for 15% of all cancer cases. Chemoresistant sub phenotypes of breast cancer remain a particular challenge. However, the rapidly-growing availability of clinical datasets, presents the scope to underpin a data-driven precision medicine-based approach exploring new targets for diagnostic...

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alpha Karyopherins
Biomarkers, Tumor
Computational Biology
Mutation
Neoplasms

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PMID: 35948941
DOI: 10.1186/s12885-022-09969-4
PMCID: PMC9364282

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