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Article

Nuclear transport receptor karyopherin-α2 promotes malignant breast cancer phenotypes in vitro.

Oncogene - 19 Apr 2012

Noetzel E, Rose M, Bornemann J, Gajewski M, Knüchel R, Dahl E

Abstract excerpt

Tumorigenesis and tumor progression are associated with dysfunction of the nuclear transport machinery at the level of import and export receptors (karyopherins). Recent studies have shown that the nuclear import factor karyopherin-α2 (KPNA2) is a novel prognostic marker for poor prognosis in human breast cancer. Based on the well-defined hallmarks of cancer progression, we performed a detailed in vitro...

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Source

Identifiers

PMID: 21909132
DOI: 10.1038/onc.2011.403

Genes

KPNA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nuclear transport receptor karyopherin-α2 promotes malignant breast cancer phenotypes in vitro.PMID 21909132Read ↗

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