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The role of metagenomic next-generation sequencing in the pathogen detection of invasive osteoarticular infection

29 Jul 2022

Abstract excerpt

OBJECTIVES: This study aimed to analyze the pathogenic bacteria spectrum in invasive and primary osteoarticular infection (IOI and POI) and compare the pathogen detection rate of metagenomic next-generation sequencing (mNGS) and microbial culture in IOI and POI. METHODS: The suspected POI and IOI cases from 2014-2021 were included. The diagnosis of POI or IOI was made by at least two orthopedic surgeons, two...

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PMID: 35908720
DOI: 10.1016/j.ijid.2022.07.061

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