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Metagenomic Next-Generation Sequencing Improves Pathogen Detection and Rational Use in Patients with Infectious Fever: A Retrospective Study

2026-08-20

Abstract excerpt

<title>Abstract</title> <p> <italic> <bold>Objective</bold> </italic> <italic>:</italic> To compare the diagnostic performance of metagenomic next‑generation sequencing (mNGS) and conventional microbiological tests (CMTs) in infectious fever, and to explore optimal specimen types, predictive biomarkers, and clinical scenarios for rational mNGS utilization. <italic> <bold>Methods:</bold> </italic> <italic...

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Literature Corpus work
06319cdc-2f80-529a-9fd2-7ef40bfc7c63
DOI
10.21203/rs.3.rs-10327479/v1
Open publication

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Metagenomic Next-Generation Sequencing Improves Pathogen Detection and Rational Use in Patients with Infectious Fever: A Retrospective StudyDOI 10.21203/rs.3.rs-10327479/v1
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