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Metagenomic next-generation sequencing promotes pathogen detection over culture in joint infections with previous antibiotic exposure

26 Aug 2024

Abstract excerpt

Objective To investigate the diagnostic value of metagenomic next-generation sequencing (mNGS) in detecting pathogens from joint infection (JI) synovial fluid (SF) samples with previous antibiotic exposure. Methods From January 2019 to January 2022, 59 cases with suspected JI were enrolled. All cases had antibiotic exposure within 2 weeks before sample collection. mNGS and conventional culture were performed on...

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PMID: 39253328
DOI: 10.3389/fcimb.2024.1388765

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