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Evaluation of 16S-Based Metagenomic NGS as Diagnostic Tool in Different Types of Culture-Negative Infections

30 Aug 2024

Abstract excerpt

Bacterial infections pose significant global health challenges, often underestimated due to difficulties in accurate diagnosis, especially when culture-based diagnostics fail. This study assesses the effectiveness of 16S-based metagenomic next generation sequencing (NGS) for identifying pathogens in culture-negative clinical samples across various medical settings. Overall, 48% of samples were collected from...

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Infective Endocarditis Diagnosis and Management
Orthopedic Infections and Treatments
Respiratory viral infections research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39338934
DOI: 10.3390/pathogens13090743

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