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Molecular pathology and biomarker of progression in Alzheimer’s disease

1 Jul 2022

Abstract excerpt

We know so much and yet we don’t. What has been learnt about the complex molecular pathology of Alzheimer’s disease and its implications for treatment is without doubt impressive.1–4 We now even have diagnostic CSF and plasma biomarkers based on this knowledge.5 Despite this, there is a sense of unease. Do we really understand the fundamental mechanisms that lead to cognitive decline in Alzheimer’s disease or are...

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PMID: 35905467
DOI: 10.1093/brain/awac209

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