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Article

DJ-1 controls T cell differentiation and osteoclastogenesis in rheumatoid arthritis

27 Jul 2022

Abstract excerpt

Abstract Herein, we investigated the effect of DJ-1 on helper T cell differentiation, fibroblast-like synoviocyte (FLS) activation, and osteoclastogenesis in rheumatoid arthritis (RA). Serum and synovial fluid (SF) of RA and osteoarthritis (OA) patients were collected, and DJ-1 and H2O2 levels were investigated. CD4+ cells from peripheral blood mononuclear cells (PBMCs) were cultured under type 17 helper T cell...

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PMID: 35896699
DOI: 10.1038/s41598-022-16285-1

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