Article
Immune biomarker differences and changes comparing HCV mono-infected, HIV/HCV co-infected, and HCV spontaneously cleared patients.
PloS one - 1 Jan 2013
Kushner Lauren E, Wendelboe Aaron M, Lazzeroni Laura C, Chary Aarthi, Winters Mark A, Osinusi Anu, Kottilil Shyam, Polis Michael A, Holodniy Mark
Abstract excerpt
BACKGROUND: Immune biomarkers are implicated in HCV treatment response, fibrosis, and accelerated pathogenesis of comorbidities, though only D-dimer and C-reactive protein have been consistently studied. Few studies have evaluated HIV/HCV co-infection, and little longitudinal data exists describing a broader antiviral cytokine response. METHODS: Fifty immune biomarkers were analyzed at baseline (BL) and HCV end...
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