Article
High prevalence of hepatitis B virus pre-s mutant in countries where it is endemic and its relationship with genotype and chronicity.
Journal of clinical microbiology - 1 Dec 2003
Huy Tran Thien-Tuan, Ushijima Hiroshi, Win Khin Maung, Luengrojanakul Pairoj, Shrestha Pradeep Krishna, Zhong Zhao-Hua, Smirnov Andrei V, Taltavull Teresa Casanovas, Sata Tetsutaro, Abe Kenji
Abstract excerpt
It has been reported that hepatitis B virus (HBV) mutants carrying mutations in the pre-S region can be found in infected patients. In this study, we investigated the prevalence of the HBV variant with the pre-S mutant in different geographic regions, including countries with low and high levels of endemic HBV infection, and analyzed the correlation with clinical findings. We examined 387 HBV DNA-positive serum...
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