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Insights on the Modulation of SIRT5 Activity: A Challenging Balance

12 Jul 2022

Abstract excerpt

SIRT5 is a member of the Sirtuin family, a class of deacetylating enzymes consisting of seven isoforms, involved in the regulation of several processes, including gene expression, metabolism, stress response, and aging. Considering that the anomalous activity of SIRT5 is linked to many pathological conditions, we present herein an overview of the most interesting modulators, with the aim of contributing to...

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PMID: 35889322
DOI: 10.3390/molecules27144449

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