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Estimations of Mutation Rates Depend on Population Allele Frequency Distribution: The Case of Autosomal Microsatellites.

Genes - 14 Jul 2022

Antão-Sousa Sofia, Conde-Sousa Eduardo, Gusmão Leonor, Amorim António, Pinto Nádia

Abstract excerpt

Microsatellites (or short-tandem repeats (STRs)) are widely used in anthropology and evolutionary studies. Their extensive polymorphism and rapid evolution make them the ideal genetic marker for dating events, such as the age of a gene or a population. This usage requires the estimation of mutation rates, which are usually estimated by counting the observed Mendelian incompatibilities in one-generation familial...

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Identifiers

PMID: 35886031
DOI: 10.3390/genes13071248
PMCID: PMC9323320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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