Estimation of mutation rates from parentage exclusion data: applications to STR and VNTR loci.

doi:10.1016/0027-5107(96)00014-0

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Article

Estimation of mutation rates from parentage exclusion data: applications to STR and VNTR loci.

Mutation research - 5 Jul 1996

Chakraborty R, Stivers D N, Zhong Y

Abstract excerpt

Nonpaternity is a common source of bias in estimating mutation rates when they are obtained from family data showing discordance of parental and children's genotypes. With the availability of hypervariable DNA markers, this source of bias can be largely eliminated. However, the proportion of case...

Topics

Chromosome Mapping
Female
Humans
Male
Mutation
Repetitive Sequences, Nucleic Acid

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