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Fitness effects of bla CTX-M-15-harbouring F2:A1:B− plasmids on their native Escherichia coli ST131 H 30Rx hosts

26 Jul 2022

Abstract excerpt

OBJECTIVES: To investigate the fitness effects of large blaCTX-M-15-harbouring F2:A1:B- plasmids on their native Escherichia coli ST131 H30Rx hosts. METHODS: We selected five E. coli ST131 H30Rx isolates of diverse origin, each carrying an F2:A1:B- plasmid with the blaCTX-M-15 gene. The plasmid was eliminated from each isolate by displacement using an incompatible curing plasmid, pMDP5_cureEC958. WGS was...

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PMID: 35880751
DOI: 10.1093/jac/dkac250

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