Article
Success of Escherichia coli O25b:H4 Sequence Type 131 Clade C Associated with a Decrease in Virulence.
Infection and immunity - 16 Nov 2020
Duprilot Marion, Baron Alexandra, Blanquart François, Dion Sara, Pouget Cassandra, Lettéron Philippe, Flament-Simon Saskia-Camille, Clermont Olivier, Denamur Erick, Nicolas-Chanoine Marie-Hélène
Abstract excerpt
Escherichia coli O25b:H4 sequence type 131 (ST131), which is resistant to fluoroquinolones and which is a producer of CTX-M-15, is globally one of the major extraintestinal pathogenic E. coli (ExPEC) lineages. Phylogenetic analyses showed that multidrug-resistant ST131 strains belong to clade C, which recently emerged from clade B by stepwise evolution. It has been hypothesized that features other than multidrug...
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