Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell transcriptomes underscore genetically distinct tumor characteristics and microenvironment for hereditary kidney cancers

25 May 2022

Abstract excerpt

Our understanding of how each hereditary kidney cancer adapts to its tissue microenvironment is incomplete. Here, we present single-cell transcriptomes of 108,342 cells from patient specimens including from six hereditary kidney cancers. The transcriptomes displayed distinct characteristics of the cell of origin and unique tissue microenvironment for each hereditary kidney cancer. Of note, hereditary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Renal and related cancers
Share to Renal cell carcinoma treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35874919
DOI: 10.1016/j.isci.2022.104463

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell transcriptomes underscore genetically distinct tumor characteristics and microenvironment for hereditary kidney cancersPMID 35874919Read ↗

An Integrated Atlas of the Human Kidney Spanning Health and DiseasesSemantic proximity Read ↗

Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors.Semantic proximity Read ↗

Single-cell analyses of renal cell cancers reveal insights into tumor microenvironment, cell of origin, and therapy responseSemantic proximity Read ↗

Dissecting order amidst chaos of programmed cell deaths: construction of a diagnostic model for KIRC using transcriptomic information in blood-derived exosomes and single-cell multi-omics data in tumor microenvironmentSemantic proximity Read ↗

Distinct genomic, microenvironmental, and nephron signatures in VHL kidney cysts and tumors.Semantic proximity Read ↗

Single-nucleus sequencing unveils heterogeneity in renal cell carcinomas microenvironment: Insights into pathogenic origins and treatment-responsive cellular subgroupsSemantic proximity Read ↗

An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneitySemantic proximity Read ↗

Inter- and intra-tumor heterogeneity of genetic and immune profiles in inherited renal cell carcinoma.Semantic proximity Read ↗

Pan-urologic cancer genomic subtypes that transcend tissue of origin.Semantic proximity Read ↗

Clinicopathologic and Molecular Pathology of Collecting Duct Carcinoma and Related Renal Cell CarcinomasSemantic proximity Read ↗

Single-cell chromatin accessibility landscape in kidney identifies additional cell-of-origin in heterogenous papillary renal cell carcinomaSemantic proximity Read ↗

Integrative genomics uncover mechanisms of renal medullary carcinoma transformation, microenvironment landscape and therapeutic vulnerabilitiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.