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Article

Low IL7R Expression at Diagnosis Predicted Relapse in Adult Acute Myeloid Leukemia Patients With t(8;21).

Frontiers in immunology - 1 Jan 2022

Xu Nan, Sun Kai, Wang Ya-Zhe, Chen Wen-Min, Wang Jun, Li Ling-Di, Wang Xu, Hao Yue, Chang Yan, Liu Yan-Rong, Huang Xiao-Jun, Qin Ya-Zhen

Abstract excerpt

Background: Acute myeloid leukemia (AML) with t(8;21) needs to be further stratified. In addition to leukemia cells, immune cells in tumor microenvironment participate in tumor initiation, growth and progression. Interleukins (ILs)/interleukin receptors (ILRs) interaction plays important roles in the antitumor immune response. IL7R is reported to be relevant to prognosis in solid tumor and acute lymphoblastic...

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Share to Antigens, CD
Share to Antigens, Differentiation, Myelomonocytic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD8-Positive T-Lymphocytes

Share to Interleukin-7 Receptor alpha Subunit

Share to Leukemia, Myeloid, Acute

Share to Promoter Regions, Genetic

Share to Recurrence

Share to Tumor Microenvironment

Source

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Identifiers

PMID: 35874754
DOI: 10.3389/fimmu.2022.909104
PMCID: PMC9302488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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