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Synchronizing spermatogenesis in the mouse

24 Jul 2022

Abstract excerpt

The formation of spermatozoa starts with a germ-line stem cell creating a pool of progenitor cells or undifferentiated spermatogonia. There is a requirement for these progenitor cells to be stimulated by retinoic acid (RA) to enter differentiation and ultimately form spermatocytes, undergo meiosis, form spermatids, and ultimately spermatozoa. After the stimulation by RA, which occurs at sites in the seminiferous...

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PMID: 35871549
DOI: 10.1093/biolre/ioac148

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