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Article

ANKLE2 ‐related microcephaly: A variable microcephaly syndrome resembling Zika infection

24 Jul 2022

Abstract excerpt

OBJECTIVE: This study delineates the clinical and molecular spectrum of ANKLE2-related microcephaly (MIC), as well as highlights shared pathological mechanisms between ANKLE2 and the Zika virus. METHODS: We identified 12 individuals with MIC and variants in ANKLE2 with a broad range of features. Probands underwent thorough phenotypic evaluations, developmental assessments, and anthropometric measurements. Brain...

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Biological Research and Disease Studies
Infectious Encephalopathies and Encephalitis
Mosquito-borne diseases and control

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35871307
DOI: 10.1002/acn3.51629

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