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Article

DNA methylation subclasses predict the benefit from gross total tumor resection in IDH-wildtype glioblastoma patients

22 Jul 2022

Abstract excerpt

BACKGROUND: DNA methylation-based tumor classification allows an enhanced distinction into subgroups of glioblastoma. However, the clinical benefit of DNA methylation-based stratification of glioblastomas remains inconclusive. METHODS: Multicentric cohort study including 430 patients with newly diagnosed glioblastoma subjected to global DNA methylation profiling. Outcome measures included overall survival (OS),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35868257
DOI: 10.1093/neuonc/noac177

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