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HLA-DRB1∗1502 Is Associated With Anti-N-Methyl-D-aspartate Receptor Encephalitis in Thai Children.

Pediatric neurology - 1 Sept 2022

Anurat Kingthong, Watcharakuldilok Piangor, Sakpichaisakul Kullasate, Khongkhatithum Chaiyos, Mahasirimongkol Surakameth, Kunhapan Punna, Inunchot Wimala, Wattanapokayakit Sukanya, Munggaranonchai Orathai, Thampratankul Lunliya

Abstract excerpt

BACKGROUND: Anti-N-methyl-d-aspartate receptor encephalitis (anti-NMDARE) is one of the most common types of autoimmune encephalitis. Most patients have no apparent immunologic triggers, which suggests a genetic predisposition. This study was conducted to identify human leukocyte antigen (HLA) class II alleles associated with anti-NMDARE in Thai children. METHODS: This case-control study enrolled patients younger...

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PMID: 35863207
DOI: 10.1016/j.pediatrneurol.2022.06.014

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