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Article

Single-Cell Mass Spectrometry Enables Insight into Heterogeneity in Infectious Disease

21 Jul 2022

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide Cellular heterogeneity is generally overlooked in infectious diseases. In this study, we investigated host cell heterogeneity during infection with Trypanosoma cruzi ( T. cruzi ) parasites, causative agents of Chagas disease (CD). In chronic-stage CD, only a few host cells are infected with a large load of parasites and symptoms may appear at sites distal to...

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PMID: 35863111
DOI: 10.1021/acs.analchem.2c02279

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